Melanoma Pictures: Skin Changes and What to Look For Vulvar Melanotic Macules DoveMed Clinical features of cutaneous melanotic nevihead and neck region. a Download Scientific Diagram Oral Melanotic Macule: Symptoms and Treatment Skinsight Despite the name "melanosis," the pigment isn't melanin. The Pigment: It is actually lipofuscin, a "wear and tear" pigment. The Process: Anthraquinone laxatives cause apoptosis (cell death) of the colonic epithelial cells. From melanocytes to melanomas Nature Reviews Cancer