Pathology of G6PD deficiency Pathology Made Simple Although G6PD deficiency, which can cause problems in red blood cells upon certain triggers, is the most common human enzyme defect, affecting over 400 million people, including over 1 in 10 Black HEMOLYTIC ANEMIA The Pentose Phosphate Pathway & G6PD Deficiency , Blog: https: bit.ly pentosephosphatepathway; https: bit.ly g6pddeficiency, YouTube: https: youtu.be ITy2gkUD7eM , Key points about the Pentose Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst Safe fluoroquinolones prophylaxis in blood cancer patients with chemotherapyinduced neutropenia and Glucose6PhosphateDehydrogenase deficiency Sanna 2017 Journal of Clinical Pharmacy and Therapeutics Wiley Online Library