How B12 & Lipo Injections Support Weight Loss Efforts Instruction Guide for Intramuscular (IM) Self injection of B12 Methylcobalamin 1mg 5mg Sites of Administration of Subcutaneous injection Figure. Anatomical markers used to identify the vastus lateralis injection site on the anterolateral thigh The Australian Immunisation Handbook Safe IM Injection Site Intramuscular injection should always be given in the **upper outer quadrant of the gluteal region** to prevent sciatic nerve injury. Key nursing points: Upper outer quadrant = Optimal B12 Injection Sites for Maximum Absorption and Benefits Your Health Magazine