New in the August 14, 2025, issue of NEJM: CagrilintideSemaglutide for Overweight or Obesity (REDEFINE 1 phase 3a trial) Cagrilintide Semaglutide for Overweight and Diabetes (REDEFINE 2 phase 3a trial) Obesity pharmacotherapy in older adults: a narrative review of evidence International Journal of Obesity PDF] Once weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double blind, placebo controlled and active controlled, dose finding phase 2 trial. Semantic Scholar Cagrilintide Wikipedia CagriSema in Clinical Trials: What Patients Should Know Cagrilintide & Semaglutide in Overweight Diabetics (REDEFINE 2) NEJM Med Journal Club
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coadministered cagrilintide and semaglutide in adults with overweight or obesity Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has well-established weight-loss benefits. Cagrilintide, a long-acting analogue of the satiety hormone amylin, has shown promise for weight loss in early trials. The potential benefit