The Redox Process in Red Blood Cells: Balancing Oxidants and Antioxidants Response of Human Red Blood Cells to Acute and Chronic Oxidant Challenge as Observed Through the Glutathione and Glutathionyl Hemoglobin Redox Pairs In Vitro and In Vivo Simplify your Glutathione Measurements Arbor Assays Rasburicase Induced Hemolytic Anemia Secondary to Undiagnosed G6PD Deficiency Published in Journal of Brown Hospital Medicine In RBCs, NADPH are produced exclusively via HMP shunt by the action of G6PD and are responsible to maintain membrane integrity preventing premature destruction. That is why G6PD deficient RBCs are Glutathione Synthesis and Turnover in the Human Erythrocyte Journal of Biological Chemistry