Understanding Lip Spot Causes and Treatments Treatment of labial melanotic macules on the lip. These are benign spots that appear on the lips for no apparent reason. The causes are mostly genetic, but similar spots can appear in Melanotic Macules, Naevi, and Melanoma Springer Nature Link Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review Does anyone know what this black mark on my lip is? Started last August so it's I've had it nearly a year, was living in Spain at the time for 6 months Labial Melanotic Macules in Atopic Dermatitis: An Observational Study Semantic Scholar